Honda rider Marquez made the proper launch from pole place to make a break firstly, opening up a one-second lead over a equally fast-starting Valentino Rossi on the primary tour.
The reigning champion then started to set a fearsome tempo that none of his rivals might match, stretching his benefit to 3 seconds after three laps.
After 10 of 25 laps, Marquez was a full seven seconds within the clear, and his lead peaked at greater than 12 seconds within the latter phases earlier than he lastly crossed the road with 9.8s in his pocket for his third win at Termas de Rio Hondo.
Behind, the battle for second was fought largely between Rossi and Dovizioso, with Yamaha rider Rossi recovering from working huge at Turn 5 on lap seven to retake the place the next tour.
Dovizioso discovered a approach again by his countryman on lap 13, however was unable to flee Rossi, who dived again previous the Italian at Turn 7 on the ultimate lap to come back residence second.
A frenetic scrap for fourth place went the way in which of Jack Miller, after the Pramac Ducati rider made late passes on Alex Rins – up from 16th on the grid – and the second works Ducati of Danilo Petrucci.
Rossi’s teammate Maverick Vinales made a poor begin from second on the grid to drop to fourth on the opening lap, after which slumped to eighth on lap two.
The Spaniard regarded set to take seventh place earlier than being taken out by the Petronas SRT Yamaha of Franco Morbidelli on the final lap at Turn 7.
That accident promoted Takaaki Nakagami (LCR Honda) to seventh forward of Fabio Quartararo (Petronas), Aleix Espargaro (Aprilia) and Pol Espargaro (KTM).
Behind Tech three KTM rookie Miguel Oliveira, Jorge Lorenzo introduced residence the second Repsol Honda in 12th, the identical place he certified, recovering some positions after dropping out of the factors early on.
Cal Crutchlow (LCR Honda) blew a robust probability to be a part of the rostrum struggle with a jump-start, incomes himself a ride-through penalty that left him down in 13th.
Johann Zarco completed 15th for the second race in a row on the second of the works KTMs, whereas Andrea Iannone (Aprilia) was final of the finishers in 17th.
Both Avintia Ducatis of Tito Rabat and Karel Abraham crashed out, whereas Suzuki’s Joan Mir retired within the pits after a lurid grass-tracking second late within the race.
Race outcomes: